KEGG pathway name : Longevity regulating pathway
gene symbol INSR species H.sapiens chromosome 19
protein Name insulin receptor preproprotein num of AS variants 3
AS position Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map (*)

(* In the map, this protein is shown in yellow along with other proteins subjected to AS shown in pink.)


other proteins subjected to AS in Longevity regulating pathway
1 gene symbol TSC1 species H.sapiens chromosome 9
protein Name hamartin num of AS variants 4
AS position Mid
C-ter		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map

2 gene symbol STK11 species H.sapiens chromosome 19
protein Name serine/threonine-protein kinase STK11 num of AS variants 4
AS position Mid
C-ter		 AS type SUB 3D data on AS Available
link View this protein in the KEGG pathway map

3 gene symbol TP53 species H.sapiens chromosome 17
protein Name cellular tumor antigen p53 num of AS variants 18
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

4 gene symbol TSC2 species H.sapiens chromosome 16
protein Name tuberin num of AS variants 10
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map

5 gene symbol SOD2 species H.sapiens chromosome 6
protein Name superoxide dismutase [Mn], mitochondrial precursor num of AS variants 7
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

6 gene symbol IGF1R species H.sapiens chromosome 15
protein Name insulin-like growth factor 1 receptor precursor num of AS variants 2
AS position Mid AS type INDEL 3D data on AS -
link View this protein in the KEGG pathway map

7 gene symbol IGF1 species H.sapiens chromosome 12
protein Name insulin-like growth factor I preproprotein num of AS variants 5
AS position N-ter
C-ter		 AS type SUB 3D data on AS -
link View this protein in the KEGG pathway map

8 gene symbol ADCY7 species H.sapiens chromosome 16
protein Name adenylate cyclase type 7 num of AS variants 6
AS position C-ter AS type SUB 3D data on AS Available
link View this protein in the KEGG pathway map

9 gene symbol ADCY8 species H.sapiens chromosome 8
protein Name adenylate cyclase type 8 num of AS variants 3
AS position N-ter
Mid		 AS type INDEL 3D data on AS Available
link View this protein in the KEGG pathway map

10 gene symbol HRAS species H.sapiens chromosome 11
protein Name GTPase HRas num of AS variants 3
AS position N-ter
C-ter		 AS type SUB 3D data on AS Available
link View this protein in the KEGG pathway map

11 gene symbol NFKB1 species H.sapiens chromosome 4
protein Name nuclear factor NF-kappa-B p105 subunit proprotein num of AS variants 4
AS position N-ter
Mid		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

12 gene symbol ADCY4 species H.sapiens chromosome 14
protein Name adenylate cyclase type 4 num of AS variants 6
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

13 gene symbol SESN1 species H.sapiens chromosome 6
protein Name sestrin-1 num of AS variants 3
AS position N-ter AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

14 gene symbol ATF2 species H.sapiens chromosome 2
protein Name cyclic AMP-dependent transcription factor ATF-2 num of AS variants 12
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

15 gene symbol FOXO3 species H.sapiens chromosome 6
protein Name forkhead box protein O3 num of AS variants 2
AS position N-ter AS type INDEL 3D data on AS Available
link View this protein in the KEGG pathway map

16 gene symbol AKT2 species H.sapiens chromosome 19
protein Name RAC-beta serine/threonine-protein kinase num of AS variants 11
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

17 gene symbol CAMK4 species H.sapiens chromosome 5
protein Name calcium/calmodulin-dependent protein kinase type IV num of AS variants 5
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

18 gene symbol EIF4E species H.sapiens chromosome 4
protein Name eukaryotic translation initiation factor 4E num of AS variants 5
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

19 gene symbol PRKACA species H.sapiens chromosome 19
protein Name cAMP-dependent protein kinase catalytic subunit alpha num of AS variants 5
AS position N-ter
C-ter		 AS type SUB 3D data on AS Available
link View this protein in the KEGG pathway map

20 gene symbol PRKACB species H.sapiens chromosome 1
protein Name cAMP-dependent protein kinase catalytic subunit beta num of AS variants 17
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

21 gene symbol PRKAG1 species H.sapiens chromosome 12
protein Name 5'-AMP-activated protein kinase subunit gamma-1 num of AS variants 7
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

22 gene symbol RPS6KB1 species H.sapiens chromosome 17
protein Name ribosomal protein S6 kinase beta-1 num of AS variants 8
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

23 gene symbol PIK3R3 species H.sapiens chromosome 1
protein Name phosphatidylinositol 3-kinase regulatory subunit gamma num of AS variants 4
AS position N-ter
Mid		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

24 gene symbol RPS6KB2 species H.sapiens chromosome 11
protein Name ribosomal protein S6 kinase beta-2 num of AS variants 6
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

25 gene symbol ADCY3 species H.sapiens chromosome 2
protein Name adenylate cyclase type 3 num of AS variants 5
AS position Mid AS type INDEL 3D data on AS Available
link View this protein in the KEGG pathway map

26 gene symbol ATF6B species H.sapiens chromosome 6
protein Name cyclic AMP-dependent transcription factor ATF-6 beta num of AS variants 2
AS position Mid AS type INDEL 3D data on AS -
link View this protein in the KEGG pathway map

27 gene symbol EIF4E2 species H.sapiens chromosome 2
protein Name eukaryotic translation initiation factor 4E type 2 num of AS variants 7
AS position Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

28 gene symbol ATG5 species H.sapiens chromosome 6
protein Name autophagy protein 5 num of AS variants 8
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

29 gene symbol MTOR species H.sapiens chromosome 1
protein Name serine/threonine-protein kinase mTOR num of AS variants 3
AS position N-ter AS type INDEL 3D data on AS Available
link View this protein in the KEGG pathway map

30 gene symbol PIK3CD species H.sapiens chromosome 1
protein Name phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform num of AS variants 4
AS position Mid AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

31 gene symbol PIK3R2 species H.sapiens chromosome 19
protein Name phosphatidylinositol 3-kinase regulatory subunit beta num of AS variants 2
AS position C-ter AS type SUB 3D data on AS Available
link View this protein in the KEGG pathway map

32 gene symbol AKT1 species H.sapiens chromosome 14
protein Name RAC-alpha serine/threonine-protein kinase num of AS variants 3
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

33 gene symbol AKT3 species H.sapiens chromosome 1
protein Name RAC-gamma serine/threonine-protein kinase num of AS variants 3
AS position C-ter AS type SUB 3D data on AS Available
link View this protein in the KEGG pathway map

34 gene symbol RHEB species H.sapiens chromosome 7
protein Name GTP-binding protein Rheb num of AS variants 3
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

35 gene symbol PIK3CB species H.sapiens chromosome 3
protein Name phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta 1 num of AS variants 6
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

36 gene symbol PRKAA1 species H.sapiens chromosome 5
protein Name 5'-AMP-activated protein kinase catalytic subunit alpha-1 num of AS variants 3
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

37 gene symbol PRKAA2 species H.sapiens chromosome 1
protein Name 5'-AMP-activated protein kinase catalytic subunit alpha-2 num of AS variants 2
AS position Mid AS type SUB 3D data on AS Available
link View this protein in the KEGG pathway map

38 gene symbol PRKAB1 species H.sapiens chromosome 12
protein Name 5'-AMP-activated protein kinase subunit beta-1 num of AS variants 3
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

39 gene symbol CAMKK2 species H.sapiens chromosome 12
protein Name calcium/calmodulin-dependent protein kinase kinase 2 num of AS variants 9
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

40 gene symbol EHMT2 species H.sapiens chromosome 6
protein Name histone-lysine N-methyltransferase EHMT2 num of AS variants 6
AS position N-ter
Mid		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

41 gene symbol SIRT1 species H.sapiens chromosome 10
protein Name NAD-dependent protein deacetylase sirtuin-1 num of AS variants 3
AS position N-ter AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

42 gene symbol PPARGC1A species H.sapiens chromosome 4
protein Name peroxisome proliferator-activated receptor gamma coactivator 1-alpha num of AS variants 7
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map

43 gene symbol RB1CC1 species H.sapiens chromosome 8
protein Name RB1-inducible coiled-coil protein 1 num of AS variants 2
AS position Mid AS type INDEL 3D data on AS -
link View this protein in the KEGG pathway map

44 gene symbol ADCY6 species H.sapiens chromosome 12
protein Name adenylate cyclase type 6 num of AS variants 2
AS position Mid AS type INDEL 3D data on AS -
link View this protein in the KEGG pathway map

45 gene symbol PPARG species H.sapiens chromosome 3
protein Name peroxisome proliferator-activated receptor gamma num of AS variants 9
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

46 gene symbol PRKAG2 species H.sapiens chromosome 7
protein Name 5'-AMP-activated protein kinase subunit gamma-2 num of AS variants 9
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

47 gene symbol PRKAG3 species H.sapiens chromosome 2
protein Name 5'-AMP-activated protein kinase subunit gamma-3 num of AS variants 3
AS position Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

48 gene symbol RPTOR species H.sapiens chromosome 17
protein Name regulatory-associated protein of mTOR num of AS variants 5
AS position Mid
C-ter		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map

49 gene symbol ADCY1 species H.sapiens chromosome 7
protein Name adenylate cyclase type 1 num of AS variants 2
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map

50 gene symbol RELA species H.sapiens chromosome 11
protein Name transcription factor p65 num of AS variants 13
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

51 gene symbol EHMT1 species H.sapiens chromosome 9
protein Name histone-lysine N-methyltransferase EHMT1 num of AS variants 13
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

52 gene symbol AKT1S1 species H.sapiens chromosome 19
protein Name proline-rich AKT1 substrate 1 num of AS variants 2
AS position N-ter AS type INDEL 3D data on AS -
link View this protein in the KEGG pathway map

53 gene symbol CREB3L3 species H.sapiens chromosome 19
protein Name cyclic AMP-responsive element-binding protein 3-like protein 3 num of AS variants 4
AS position Mid
C-ter		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map

54 gene symbol KRAS species H.sapiens chromosome 12
protein Name GTPase KRas num of AS variants 4
AS position C-ter AS type SUB 3D data on AS Available
link View this protein in the KEGG pathway map

55 gene symbol CREB3L1 species H.sapiens chromosome 11
protein Name cyclic AMP-responsive element-binding protein 3-like protein 1 num of AS variants 2
AS position C-ter AS type SUB 3D data on AS Available
link View this protein in the KEGG pathway map

56 gene symbol CREB3L4 species H.sapiens chromosome 1
protein Name cyclic AMP-responsive element-binding protein 3-like protein 4 num of AS variants 4
AS position Mid
C-ter		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map

57 gene symbol CREB1 species H.sapiens chromosome 2
protein Name cyclic AMP-responsive element-binding protein 1 num of AS variants 5
AS position Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

58 gene symbol BAX species H.sapiens chromosome 19
protein Name apoptosis regulator BAX num of AS variants 11
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

59 gene symbol SESN3 species H.sapiens chromosome 11
protein Name sestrin-3 num of AS variants 3
AS position N-ter
Mid
C-ter		 AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

60 gene symbol PIK3R1 species H.sapiens chromosome 5
protein Name phosphatidylinositol 3-kinase regulatory subunit alpha num of AS variants 6
AS position N-ter AS type INDEL
SUB		 3D data on AS Available
link View this protein in the KEGG pathway map

61 gene symbol CREB5 species H.sapiens chromosome 7
protein Name cyclic AMP-responsive element-binding protein 5 num of AS variants 6
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map

62 gene symbol ADCY5 species H.sapiens chromosome 3
protein Name adenylate cyclase type 5 num of AS variants 4
AS position N-ter
Mid		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map

63 gene symbol CREB3L2 species H.sapiens chromosome 7
protein Name cyclic AMP-responsive element-binding protein 3-like protein 2 num of AS variants 7
AS position N-ter
C-ter		 AS type INDEL
SUB		 3D data on AS -
link View this protein in the KEGG pathway map